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Molecular formula: C18H1CrN3O6, Molecular weight 418.31, CAS No. 14639-25-9. Physical properties: Purple-red crystalline powder, stable at room temperature, slightly soluble in water (about 3.28 mg/L), insoluble in ethanol, resistant to high-temperature processing (such as feed pelletizing). Structural features: The electrically neutral chelate formed by trivalent chromium (Cr³+) and pyridylic acid has strong hydrophobicity and can be completely absorbed through the cell membrane, with a bioavailability of 2%-5%, significantly higher than that of common chromium preparations (0.5%). |
Weight management
Clinical studies have shown that 200 mg per day can reduce body fat by 2.2% by enhancing insulin sensitivity, promoting fat metabolism and glucose utilization.
Inhibit the appetite receptors T1R2/T1R3 to reduce the craving for sweet foods.
Blood sugar control
Activate the p38 MAPK pathway, enhance insulin receptor activity and glucose uptake efficiency, and improve the glycated hemoglobin (HbA1c) level in patients with type 2 diabetes.
Exercise enhancement
It increases the uptake of glucose by muscles, enhances the metabolic rate and endurance during exercise, and the effect in animal experiments is three times that of capsaicin.
Cardiovascular protection
Lower blood lipids (total cholesterol, LDL), inhibit oxidative stress and inflammatory factors (such as TNF-α, IL-6), and reduce the risk of atherosclerosis.
Anti-aging
Reduce DNA damage and apoptosis, enhance the activity of antioxidant enzymes, and delay skin aging.
Food and health products
It is used as a dietary supplement for weight management or as an adjunctive treatment for diabetes
Infant formula food and dairy product fortification
Animal feed
Adding 1-2 kg/ ton of feed can increase the daily weight gain of young livestock by 200 g and reduce the diarrhea rate by 35%.
Medical research
It is used to regulate the nuclear factor NF-κB and Nrf2 pathways and explore the therapeutic potential of anti-inflammatory and metabolic diseases