Mulberry Leaf Extract Powder for Blood Sugar Control and Skin Health CAS19130-96-2

• Customization: Available
• Certification: ISO, FDA
• Assay Method: HPLC-MS, HPLC, UV
• Model NO.: Mulberry Leaf Powder
• Application Form: Paste, Tablet, Capsule, Powder
• Application: Food, Health Care Products, Medicine
• State: Powder
• Extract Source: Mulberry
• Shelf Life: 2 Years Proper Storage
• Transport Package: 25kg for Drum
• Specification: 99%
• Trademark: TZSW
• Origin: China
• Production Capacity: 5000

Product Description

Mulberry Leaf Extract powder for Blood Sugar Control and Skin Health CAS19130-96-2

Mulberry Leaf is considered as a nice herb in the ancient China for anti-inflammation, anti-aging and maintaining health. Mulberry leaf is rich in amino acids,vitamin C and antioxidants. Among this components, the most valuable are Rutoside and DNJ(1-Deoxynojimycin),The latest Chinese research has shown Rutoside and DNJ are effective in regulating blood fat, balancing blood pressure, reducing blood glucose, and boosting metabolism. SO they are widely used as raw materials for curing diabetes.
 
The leaves are mostly crimped and broken, intact ovate or broadly ovate, 8-13cm long, 7-11cm wide, apex pointed, edge serrated, sometimes divided irregularly, base truncated, round or heart-shaped: upper flower Green, slightly shiny, with fine hairs along the veins, lighter underneath, with protruding veins, small veins intertwined into a network, densely covered with fine hairs. The texture is brittle and fragile. The smell, taste is light, slightly bitter. The leaves are intact, large, thick, and yellowish-green in color. According to reports, mulberry leaves have the effects of regulating blood sugar, dispersing wind-heat, clearing lungs and moisturizing dryness, and clearing liver and improving eyesight. It is used for symptoms such as wind-heat cold, lung-heat cough, headache, dizziness, red eyes and dizziness.

Mulberry leaves have been used for thousands of years as a food material for clearing away heat. The earliest written records can be traced back to the book Shen Nongs Herbal Classic in 1800 years ago. Nowadays, mulberry leaf is included in the Medicinal and Alimental Materials List announced by the Chinese Ministry of Health, all the materials in that list is considered to be safely used as food, while they will also be helpful for human health licorice, ginger, honey, and black sesame are also in that list .

 

product name:	Mulberry Leaf Extract
Appearance:	brown
Origin	China
Grade standard:	Pharmaceutical grade
specification:	98%
Brand:	TZSW
store	Cool and dry
Shelf life	24 months

(1)  The effect to reduce blood glucose
Mulberry leaf shows the effect to reduce blood glucose for experimental rat with diabetes.  Make experiment by the white rat with diabetes.  Feed mulberry leaf and its extracts 6 - 8 weeks ago when coming down with diseases.  Last for 48 weeks, then research the effect to blood glucose.  You will see that feeding the mulberry leaf to the white rat with diabetes before diseases coming, may delay diabetes and inhibit the disease worse. 
DNJ in mulberry leaf has clear inhibition to the value of blood glucose rising.
Total polysaccharides in mulberry leaf have clear effect to reduce blood glucose for rat with diabetes caused by alloxan.
(2)  The effect to reduce blood pressure
γ-amino butanoic acid in mulberry leaf has the effect to reduce blood pressure.  Add mulberry leaf to the feed for rat with natural high blood pressure, continuously feeding several days later, you would find that the frequency of the symptom for the rat with high blood pressure decreases obviously.  This is related to the action of γ-amino butanoic acid in mulberry leaf. 
(3)  The effect to reduce biochem cholesterol and reduce blood fat
Botanic sterols in mulberry leaf can inhibit the absorption of biochem cholesterol inside intestine canal.  The flavones in mulberry leaf also can inhibit the absorption of biochem cholesterol, along with improving liver function. 
Feeding the rabbit with high blood fat, mixed with mulberry leaf, to the result, the biochem cholesterol and neutral fat in serum decrease in different degree.  Mulberry leaf and its extracts also can reduce the intensity of the protein in serum for the rabbit. 
Through study to pathologic section of the liver, it's proved that mulberry leaf has indeed the effect to inhibit the formation of the fat liver and to reduce the fat in serum 
(4)  The mechanism for mulberry leaf to reduce blood glucose
Mulberry leaf can inhibit the blood glucose rising, the major functional material is that DNJ in mulberry leaf can inhibit the activation of α-glucosaminidase, inhibit catalytic reaction of α-glucosehydrolase, thus stopping and delaying starch food decomposing into monosaccharides of glucose, fructose, etc, and clearly inhibiting blood glucose rising rapidly after food.  Glucosaminidase involved in various biologic processing, such as digestion of carbohydrate and biosynthesis of glycoprotein.DNJ is the effective inhibitor to α-glucosaminidase in all mammals. It can reduce the high blood glucose through reducing digestion of carbohydrate and absorption of glucose.  DNJ can also combine with α-glycosidases of maltase, sucrase and lactase in small intestine, thus stopping them further decomposing into monosaccharides and to be absorbed and clearly inhibiting the value of blood glucose rising rapidly.

 

 

1. Medicine and health products
• Hypoglycemic capsules: compounded with pueraria flavonoids to form "Xingpan Qingsuan", used for auxiliary treatment of type 2 diabetes (400 mg per day).
• Weight loss meal replacement: added to low GI energy bars to inhibit the activity of lipase (clinical trials show that body fat rate decreased by 5%-8% in 3 months).

2. Food industry
• Functional beverages: as a natural sweetness inhibitor, reduce the sugar content of beverages (such as sugar substitute tea).
• Fermented food: lactic acid bacteria fermented mulberry leaf powder enhances nutritional value and increases protein content to ≥20%.

3. Cosmetics
• Anti-aging essence: a formula containing 0.5% mulberry leaf flavonoids can reduce UV-induced collagen degradation and delay wrinkle formation.

4. Animal Husbandry
• Feed additives: replace soybean meal, reduce feeding costs, and improve broiler intestinal health (addition amount 5%-10%)

 

Product Parameters

 

TECHNICAL DATE SHEET
PRODUCT SPECIFICATIONS
Product Name:	Mulberry Leaf Extract
Botanic  Name:	Folium Mori
Part of plant	Leaf
Solvent extraction	Water
Country of Origin:	China
Excipent	20% maltodextrin
ANALYSIS ITEMS	SPECIFICATION	TEST METHOD
Appearance	Fine powder	Organoleptic
Color	Brown fine powder	Visual
Odour & Taste	Characteristic	Organoleptic
Identification	Identical to R.S. sample	HPTLC
Extract Ratio	4:1	TLC
Sieve Analysis	100% through 80 mesh	USP39 <786>
Loss on drying	≤ 5.0%	Eur.Ph.9.0 [2.5.12]
Total Ash	≤ 5.0%	Eur.Ph.9.0 [2.4.16]
Lead (Pb)	≤ 3.0 mg/kg	Eur.Ph.9.0<2.2.58>ICP-MS
Arsenic (As)	≤ 1.0 mg/kg	Eur.Ph.9.0<2.2.58>ICP-MS
Cadmium(Cd)	≤ 1.0 mg/kg	Eur.Ph.9.0<2.2.58>ICP-MS
Mercury(Hg)	≤ 0.1 mg/kg -Reg.EC629/2008	Eur.Ph.9.0<2.2.58>ICP-MS
Heavy metal	≤ 10.0 mg/kg	Eur.Ph.9.0<2.4.8>
Solvents Residue	Conform Eur.ph. 9.0 <5,4 > and EC European Directive 2009/32	Eur.Ph.9.0<2.4.24>
Pesticides Residues	Conform Regulations(EC) No.396/2005 including annexes and successive updates Reg.2008/839/CE	Gas Chromatography
Aerobic bacteria(TAMC)	≤1000 cfu/g	USP39 <61>
Yeast/Moulds(TAMC)	≤100 cfu/g	USP39 <61>
Escherichia coli:	Absent in 1g	USP39 <62>
Salmonella spp:	Absent in 25g	USP39 <62>
Staphylococcus aureus:	Absent in 1g
Listeria Monocytogenens	Absent in 25g
Aflatoxins B1	≤ 5 ppb -Reg.EC 1881/2006	USP39 <62>
Aflatoxins ∑ B1, B2, G1, G2	≤ 10 ppb -Reg.EC 1881/2006	USP39 <62>
Packing	Pack in paper-drums and two plastic-bags inside N.W. 25 kgs I.D.35xH51cm.
Storage	Store in a well-closed container away from moisture, light, oxygen.
Shelf Life	24 months under the conditions above and in its original packaging

 

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