| Customization: | Available |
|---|---|
| Certification: | RoHS, ISO |
| Assay Method: | GPC, HPLC, UV |
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Quercetin is a potent antioxidant and has anti-inflammatory activity, protecting cellular structures and blood vessels from the damaging effects of free radicals. It improves blood vessel strength. Quercetin inhibits the activity of catechol-O-methyltransferase that breaks down the neurotransmitter norepinephrine. This effect may lead to elevated levels of norepinephrine and an increase in energy expenditure and fat oxidation.
| Product Name: | Quercetin |
| Appearance | yellow powder |
| Specification | 10%-98% |
| CAS | 117-39-5 |
| Package | 1kg/aluminum foil bag; 25kg/drum |
| Sample | Availiable |
| Storage | Dry Place |
| Shelf life | 2 Years |
What is Liposomal Quercetin?
Liposomes are vesicles composed of lipid components such as phospholipids and have a similar biological membrane structure. Lecithin is generally derived from natural lecithin, and the most common ones are soybean lecithin and egg yolk lecithin. After further processing, these lecithins can be made into liposomes for encapsulating quercetin.
By encapsulating quercetin in liposomes, the stability, solubility and bioavailability of quercetin can be improved, making it have better application prospects in the fields of medicine and health products.
What are the differences between liposomal quercetin and quercetin?
Quercetin: It is a natural flavonoid compound with a specific molecular structure. It exists in plants in a free form or in the form of glycosides combined with sugars.
Liposomal quercetin: It is a new preparation formed by encapsulating quercetin inside liposomes. Liposomes are vesicle structures composed of phospholipid bilayers, in which quercetin is encapsulated, forming a complex similar to a cell structure.
Physical and chemical properties
Quercetin: It is insoluble in water, has limited solubility in organic solvents, and has poor stability, especially under conditions of light, high temperature, high humidity, etc., it is prone to oxidation, degradation and other reactions.
Liposomal quercetin: Due to being encapsulated by liposomes, its solubility and stability have been significantly improved. The phospholipid bilayer structure of liposomes can protect quercetin from the influence of the external environment, while making it more dispersible in water, showing properties similar to colloidal solutions.
Bioavailability
Quercetin: After oral administration, its bioavailability is low due to its low solubility and easy metabolism in the gastrointestinal tract. Most quercetin may be metabolized by intestinal flora or excreted with feces before absorption, and the amount that can actually enter the blood circulation and play a role is small.
Liposomal quercetin: The presence of liposomes helps to improve the bioavailability of quercetin. Liposomes can interact with cell membranes and enter cells more easily through endocytosis or fusion, thereby promoting the absorption of quercetin. In addition, liposomes can also protect quercetin from being metabolized prematurely in the gastrointestinal tract, allowing it to reach the site of action more effectively.
Efficacy
Quercetin: It has multiple biological activities such as antioxidant, anti-inflammatory, and anti-tumor, but due to its low bioavailability and poor stability, its efficacy is limited to a certain extent.
Liposomal quercetin: It can better exert the efficacy of quercetin. On the one hand, the improved bioavailability allows more quercetin to reach target cells and target organs; on the other hand, the targeting of liposomes allows quercetin to act more concentratedly on the lesion site, thereby enhancing its therapeutic effect. For example, in anti-tumor research, liposomal quercetin can more effectively enter tumor cells, play a role in inducing tumor cell apoptosis and inhibiting tumor growth.
What are the effects of liposomal quercetin?
1. Antioxidant: Quercetin in liposomal quercetin is a powerful antioxidant that can remove free radicals in the body, slow down cell aging, and maintain cell health and vitality.
2. Anti-inflammatory: It has a certain alleviating effect on inflammatory diseases such as arthritis and enteritis, and helps to relieve symptoms such as pain and swelling caused by inflammation.
3. Improve cardiovascular health: Through antioxidant and anti-inflammatory effects, liposomal quercetin helps protect vascular endothelial cells and prevent the occurrence and development of atherosclerosis. It can also lower blood lipid levels, inhibit platelet aggregation, and reduce the risk of thrombosis, thereby protecting the cardiovascular system and reducing the incidence and mortality of cardiovascular diseases.
4. Enhance immunity: It can regulate the function of the immune system, promote the proliferation and activity of immune cells, and improve the body's resistance.
5. Anti-tumor: Quercetin has certain anti-tumor activity, which may work through multiple pathways such as inducing tumor cell apoptosis, inhibiting tumor cell proliferation and invasion, and blocking tumor angiogenesis.
6. Protect the nervous system: It can cross the blood-brain barrier, protect neuronal cells, and reduce nerve cell damage and death. In the study of some neurodegenerative diseases such as Alzheimer's disease and Parkinson's disease, it has shown a certain potential to improve cognitive function and neurological function.
7. Improve metabolic syndrome: It helps regulate blood sugar and blood lipid metabolism, improve resistance, and has a certain improvement effect on metabolic syndrome-related diseases such as obesity and diabetes.
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