Hydroxypropyl-Beta-Cyclodextrin: Leading Solution for Flavor and Aroma Retentioncas 128446-35-5

• Customization: Available
• CAS No.: 136019-12-0
• Formula: C63h112o42
• Model NO.: Hydroxypropyl-beta-Cyclodextrin
• EINECS: \
• Packaging Material: Aluminium Foil Bag and Carton
• Storage Method: Seal and Store in a Cool, Dry Place
• Shelf Life: 2 Years
• Type: Food Additives
• Resource: Natural
• COA: Available
• MOQ: 1kg
• Sample: Avaliable
• Color: White
• Transport Package: Bag/Drum
• Specification: 25KG/Drum, 1KG/Bag
• Trademark: TZSW
• Origin: China
• Production Capacity: 5000 Kg /Per Month

Product Description

Hydroxypropyl-beta-Cyclodextrin: Leading Solution for Flavor and Aroma Retention CAS136019-12-0

HP-β-CD is a hydroxypropylated derivative of β-cyclodextrin. It is composed of 7 glucose units forming a ring structure through an α-1,4-glycosidic bond, and the hydroxyl groups (2-, 3-, and 6-positions) of β-CD are replaced by hydroxypropyl groups, which significantly improves its water solubility (solubility ≥ 50% at room temperature). Its molecular formula is (C6H10O5)7·(C3H6O)n, and its molecular weight is about 1375-1806. It is a white amorphous powder, odorless, slightly sweet, and has a melting point of 267°C. Compared with natural β-CD, the hydrophobic cavity of HP-β-CD retains the inclusion capacity, but has lower hemolytic activity and surface activity, and higher biosafety.

Product Parameters

 

 

Item		Specification	Result
Appearance		White or almost white,amorphous or crystalline powder.	Conform
ldentification	IR	Same absorption bands as USP Hydroxypropyl Betadex RS	Conform
	Clarity of solution	Positive	Conform
Molar substitution		0.40~1.50	0.67
Betadex		≤1.5%	≤0.32%
Any other single impurity		≤0.025%	Not detected
Loss on drying		≤10.0%	3.6%
Clarity of solution		1.0g/2ml water solution is clear and transparent	Conform
Conductivity		≤200μS/cm	65μS/cm
The total combined molds and yeasts count		≤10³cfu/g	<10cfu/g
Packaging and storage		≤10²cfu/g	<10cfu/g
Conclusion		The results conform to USF-NF2021 Standard

 

 

Application

1 Medical field

Drug delivery: As a solubilizer for injections, it improves the solubility and bioavailability of poorly soluble drugs (such as paclitaxel).

Sustained release and targeting: Control the drug release rate through inclusion, reduce toxic side effects, and use it in mucosal drug delivery systems (such as nasal cavity and eyes).

Antiviral research

2 Food industry

Stability and flavor improvement: Inclusion of fat-soluble vitamins and antioxidants, extending shelf life and masking odor. For example, removing cholesterol from dairy products and improving the water retention of ice cream.


3 Cosmetics and environmental protection

Cosmetics: As an emulsifier and stabilizer, it reduces the irritation of organic ingredients to the skin and enhances the permeability of active ingredients.

Environmental protection: Adsorb organic pollutants and heavy metals in water for sewage treatment