| Customization: | Available |
|---|---|
| CAS No.: | 501-98-4 |
| Formula: | C9h8o3 |
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| Chemical name: 4-hydroxycinnamic acid (4-HCA) Molecular formula: C9H8O3 Molecular weight: 164.16 CAS number: 501-98-4 Structural formula: The para-hydroxyl group (C4) of the benzene ring is connected to the acrylic acid group (CH2CH2COOH), with a conjugated double bond structure. Physical properties: Appearance: White to light yellow crystalline powder Melting point: 213-215°C Solubility: Slightly soluble in cold water (about 0.5 g/L), easily soluble in hot water, ethanol, ether and alkaline solution. |
1 Antioxidant and anti-inflammatory
Scavenges free radicals (such as DPPH, ABTS), inhibits lipid peroxidation, and has stronger antioxidant activity than vitamin C.
Inhibits the NF-κB pathway, reduces the release of inflammatory factors such as TNF-α and IL-6, and is used to relieve arthritis and skin inflammation.
2 Antimicrobial and antiviral
It has a broad-spectrum antibacterial effect on Staphylococcus aureus (MIC 32 μg/mL), Escherichia coli, etc.
Inhibits the replication of influenza virus (H1N1) and blocks the fusion of viral envelope with host cell membrane.
3 Whitening and photoprotection
Inhibits tyrosinase activity, reduces melanin production, and is used as a whitening ingredient in skin care products.
Absorbs UVB (290-320 nm) and is added to sunscreen as a natural sunscreen (concentration 0.5-2%).
4 Drug delivery and anticancer
As a prodrug carrier: connects chemotherapeutic drugs (such as paclitaxel) through ester bonds to improve targeting and water solubility.
Induce tumor cell apoptosis: activate mitochondrial pathway and inhibit the proliferation of breast cancer (MCF-7) and liver cancer (HepG2) cells.
1 Medicine and health products
Anti-inflammatory drugs: used in rheumatoid arthritis patches or oral preparations.
Dietary supplements: added to capsules or tablets as antioxidants
2 Cosmetics
Whitening essence: compounded with niacinamide and arbutin to enhance the effect of lightening spots.
Sunscreen and anti-aging: used in sunscreen and anti-wrinkle cream, synergistic with vitamin E to improve photostability.
3 Food industry
Natural preservatives: inhibit spoilage bacteria in meat products and extend shelf life.
Flavor enhancers: produce caramel aroma in baked goods, replacing artificial flavors.
4 Agriculture and environmental protection
Plant growth regulators: promote crop resistance and reduce drought stress damage.
Heavy metal adsorbents: modified for sewage treatment, adsorbing lead, cadmium and other ions
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